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In our last episode of Health Update, my M-protein level was starting to rise, indicating that the Revlimid was losing effectiveness and the multiple myeloma was staging a comeback. This is normal and expected after two years. When it got above 1.0, it would be time to switch to a second-line treatment. In the end, I got nearly three years out of the Revlimid, but the time has now come to move on:

The new treatment will consist of an oral version of my old friend Velcade teamed up with Darzalex, a monoclonal antibody that’s one of the slew of new treatments that have been approved over the past few years. I will also once again be taking the evil dex, a sleep killer marketed as a corticosteroid. During my last round of dex, I used my treatment nights to write a 40-page tutorial on special and general relativity. I can’t really say why I did that, but I’m sure it would have been a publishing sensation if I had ever published it.

Anyway, the new treatment will start in a week or so. It’s once a week for two months, then once every two weeks for two months, and then once a month. The total length of time depends on how I respond. Once the M-proteins are back under control, I’ll begin a maintenance routine which will hopefully last a couple of years. Keep your fingers crossed.

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FACT:

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Today, reader support makes up about two-thirds of our budget, allows us to dig deep on stories that matter, and lets us keep our reporting free for everyone. If you value what you get from Mother Jones, please join us with a tax-deductible donation today so we can keep on doing the type of journalism 2020 demands.

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