Common Antidepressants Associated With Lower Bone Density

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Some antidepressants appear to be associated with an increased rate of bone loss in older men and women. These SSRIs (selective serotonin reuptake inhibitors), such as Prozac, Zoloft, and Paxil, treat depression by inhibiting the protein that transports serotonin, a neurotransmitter involved in sleep and depression, reports the Journal of the American Medical Association (JAMA) via Science Daily. But serotonin may also be associated with an increased rate of bone loss in older men and women, according to two new JAMA articles. And some data suggest that SSRIs may interfere with the function of osteoclasts and osteoblasts, the cells responsible for the regular breaking down and rebuilding of bone in the body. . . So, there’s a choice for you. Depression or broken bones or both. How about looking for the root cause of the depression, not just the (dubious) chemistry? –JULIA WHITTY

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DEMOCRACY DOES NOT EXIST...

without free and fair elections, a vigorous free press, and engaged citizens to reclaim power from those who abuse it.

In this election year unlike any other—against a backdrop of a pandemic, an economic crisis, racial reckoning, and so much daily crazy—Mother Jones' journalism is driven by one simple question: Will America will move closer to, or further from, justice and equity in the years to come?

If you're able to, please join us in this mission with a donation today. Our reporting right now is focused on voting rights and election security, corruption, disinformation, racial and gender equity, and the climate crisis. We can’t do it without the support of readers like you, and we need to give it everything we've got between now and November. Thank you.

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